Thyroid Hormone-dependent Epigenetic Suppression of Herpes Simplex Virus-1 Gene Expression and Viral Replication in Differentiated Neuroendocrine Cells

A global HSV-1 gene repression occurs during latency in sensory neurons where most viral gene transcriptions are suppressed. The molecular mechanisms of gene silencing and how stress factors trigger the reactivation are not well understood. Thyroid hormones are known to be altered due to stress, and...

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Bibliographic Details
Published in:J Neurol Sci
Main Authors: Figliozzi, Robert W., Chen, Feng, Balish, Matthew, Ajavon, Amakoe, Hsia, S. Victor
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252976/
https://ncbi.nlm.nih.gov/pubmed/25175854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2014.08.017
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