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Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease

Currently, there are no available approaches to cure or slow down the progression of Alzheimer’s disease (AD), which is characterized by the accumulation of extracellular amyloid-β (Aβ) deposits and intraneuronal tangles composed of hyperphosphorylated tau. β2 adrenergic receptors (β2ARs) are expres...

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Bibliografiska uppgifter
I publikationen:Neurobiol Aging
Huvudupphovsmän: Branca, Caterina, Wisely, Elena V, Hartman, Lauren K, Caccamo, Antonella, Oddo, Salvatore
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252846/
https://ncbi.nlm.nih.gov/pubmed/25034342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.06.011
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