Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function

Myeloid-derived suppressor cells (MDSC's), a heterogeneous population of cells capable of suppressing anti-tumor T cell function in the tumor microenvironment, represent an imposing obstacle in the development of cancer immunotherapeutics. Thus, identifying elements essential to the development...

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Veröffentlicht in:Mol Immunol
Hauptverfasser: Sahakian, Eva, Powers, John J., Chen, Jie, Deng, Susan L., Cheng, Fengdong, Distler, Allison, Woods, David M., Rock-Klotz, Jennifer, Laino, Andressa Sodre', Youn, Je-In, Woan, Karrune V., Villagra, Alejandro, Gabrilovich, Dmitry, Sotomayor, Eduardo M., Pinilla-Ibarz, Javier
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252813/
https://ncbi.nlm.nih.gov/pubmed/25155994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.08.002
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