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Experimental Therapies in the Murine Model of Globoid Cell Leukodystrophy
Globoid cell leukodystrophy (GLD), also known as Krabbe disease, is a rapidly progressing childhood lysosomal storage disorder caused by a deficiency in galactocerebrosidase (GALC). GALC-deficiency leads to the accumulation of galactosylsphingosine (psychosine), a cytotoxic lipid especially damaging...
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| Udgivet i: | Pediatr Neurol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252788/ https://ncbi.nlm.nih.gov/pubmed/25240259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pediatrneurol.2014.08.003 |
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