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Diffusion tensor imaging detects axonal injury and demyelination in the spinal cord and brain of a murine model of globoid cell leukodystrophy
Globoid cell leukodystrophy is an inherited neurodegenerative disorder caused by a deficiency of the lysosomal enzyme galactosylceramidase. In both human patients and the authentic murine Twitcher model, pathological findings include demyelination as well as axonal damage in both the central and per...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910583/ https://ncbi.nlm.nih.gov/pubmed/19650072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1420 |
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