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Diffusion tensor imaging detects axonal injury and demyelination in the spinal cord and brain of a murine model of globoid cell leukodystrophy

Globoid cell leukodystrophy is an inherited neurodegenerative disorder caused by a deficiency of the lysosomal enzyme galactosylceramidase. In both human patients and the authentic murine Twitcher model, pathological findings include demyelination as well as axonal damage in both the central and per...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hofling, A. Alex, Kim, Joong Hee, Fantz, Corinne R., Sands, Mark S., Song, Sheng-Kwei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910583/
https://ncbi.nlm.nih.gov/pubmed/19650072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1420
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