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Plasmid DNA Initiates Replication of Yellow Fever Vaccine In Vitro and Elicits Virus-Specific Immune Response in Mice

Yellow fever (YF) causes an acute hemorrhagic fever disease in tropical Africa and Latin America. To develop a novel experimental YF vaccine, we applied iDNA infectious clone technology. The iDNA represents plasmid that encodes the full-length RNA genome of 17D vaccine downstream from a cytomegalovi...

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Détails bibliographiques
Publié dans:Virology
Auteurs principaux: Tretyakova, Irina, Nickols, Brian, Hidajat, Rachmat, Jokinen, Jenny, Lukashevich, Igor S., Pushko, Peter
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252618/
https://ncbi.nlm.nih.gov/pubmed/25129436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.07.050
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