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DNA Vaccine Initiates Replication of Live Attenuated Chikungunya Virus In Vitro and Elicits Protective Immune Response in Mice

Background. Chikungunya virus (CHIKV) causes outbreaks of chikungunya fever worldwide and represents an emerging pandemic threat. Vaccine development against CHIKV has proved challenging. Currently there is no approved vaccine or specific therapy for the disease. Methods. To develop novel experiment...

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Détails bibliographiques
Auteurs principaux: Tretyakova, Irina, Hearn, Jason, Wang, Eryu, Weaver, Scott, Pushko, Peter
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038148/
https://ncbi.nlm.nih.gov/pubmed/24585894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu114
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