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DNA Vaccine Initiates Replication of Live Attenuated Chikungunya Virus In Vitro and Elicits Protective Immune Response in Mice

Background. Chikungunya virus (CHIKV) causes outbreaks of chikungunya fever worldwide and represents an emerging pandemic threat. Vaccine development against CHIKV has proved challenging. Currently there is no approved vaccine or specific therapy for the disease. Methods. To develop novel experiment...

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Main Authors: Tretyakova, Irina, Hearn, Jason, Wang, Eryu, Weaver, Scott, Pushko, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038148/
https://ncbi.nlm.nih.gov/pubmed/24585894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu114
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