Single-Agent Tenofovir versus Combination Emtricitabine/Tenofovir for Pre-Exposure Prophylaxis against HIV-1 Acquisition: A Randomized Trial

BACKGROUND: Antiretroviral pre-exposure prophylaxis (PrEP), using daily oral tenofovir disoproxil fumarate (TDF) or TDF in combination with emtricitabine (FTC/TDF), has been demonstrated to be efficacious for HIV-1 prevention. While the use of multiple antiretroviral agents is essential for effectiv...

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Detalhes bibliográficos
Publicado no:Lancet Infect Dis
Main Authors: Baeten, Jared M., Donnell, Deborah, Mugo, Nelly R., Ndase, Patrick, Thomas, Katherine K., Campbell, James D., Wangisi, Jonathan, Tappero, Jordan W., Bukusi, Elizabeth A., Cohen, Craig R., Katabira, Elly, Ronald, Allan, Tumwesigye, Elioda, Were, Edwin, Fife, Kenneth H., Kiarie, James, Farquhar, Carey, John-Stewart, Grace, Kidoguchi, Lara, Coombs, Robert W., Hendrix, Craig, Marzinke, Mark A., Frenkel, Lisa, Haberer, Jessica E., Bangsberg, David, Celum, Connie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252589/
https://ncbi.nlm.nih.gov/pubmed/25300863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(14)70937-5
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