HIV Protective Efficacy and Correlates of Tenofovir Blood Concentrations in a Clinical Trial of PrEP for HIV Prevention

BACKGROUND: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy for which adherence is a known determinant of efficacy. Blood concentrations of PrEP medications are one objective marker of adherence. METHODS: In a placebo-controlled PrEP efficacy trial of tenofovir diso...

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Hlavní autoři: Donnell, Deborah, Baeten, Jared M., Bumpus, Namandjé N., Brantley, Justin, Bangsberg, David R., Haberer, Jessica E., Mujugira, Andrew, Mugo, Nelly, Ndase, Patrick, Hendrix, Craig, Celum, Connie
Médium: Artigo
Jazyk:Inglês
Vydáno: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Témata:
Epidemiology and Prevention
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059553/
https://ncbi.nlm.nih.gov/pubmed/24784763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000172
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