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Changes in Glomerular Kidney Function among HIV-1 Uninfected Men and Women Receiving Emtricitabine/Tenofovir Disoproxil Fumarate Pre-exposure Prophylaxis: A Randomized Placebo-controlled Trial

IMPORTANCE: Tenofovir disoproxil fumarate (TDF) use has been associated with declines in the estimated glomerular filtration rate (eGFR) when used as part of antiretroviral treatment by HIV-1 infected persons, but limited data are available for risk when used as pre-exposure prophylaxis (PrEP) for H...

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Pubblicato in:JAMA Intern Med
Autori principali: Mugwanya, Kenneth K., Wyatt, Christina, Celum, Connie, Donnell, Deborah, Mugo, Nelly R., Tappero, Jordan, Kiarie, James, Ronald, Allan, Baeten, Jared M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354899/
https://ncbi.nlm.nih.gov/pubmed/25531343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2014.6786
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