β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

Ceruloplasmin is a ferroxidase that interacts with ferroportin to export cellular iron, but is not expressed in neurons. We recently reported that the amyloid precursor protein (APP) is the analogous iron-exporting chaperone for neurons and other cells. The ferroxidase activity of APP has since been...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wong, Bruce X., Tsatsanis, Andrew, Lim, Linh Q., Adlard, Paul A., Bush, Ashley I., Duce, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252103/
https://ncbi.nlm.nih.gov/pubmed/25464026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114174
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