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Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R expression at the cell surface
BACKGROUND: Arsenic trioxide (As(2)O(3)) is highly effective in treating acute promyelocytic leukemia (APL), but shows more variable therapeutic efficacy for other types of hematological malignancies. Previously, we reported that As(2)O(3) selectively eliminates pathogenic B220-expressing T cells in...
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| 出版年: | Mol Cancer |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252024/ https://ncbi.nlm.nih.gov/pubmed/25410152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-251 |
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