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Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R expression at the cell surface
BACKGROUND: Arsenic trioxide (As(2)O(3)) is highly effective in treating acute promyelocytic leukemia (APL), but shows more variable therapeutic efficacy for other types of hematological malignancies. Previously, we reported that As(2)O(3) selectively eliminates pathogenic B220-expressing T cells in...
Enregistré dans:
| Publié dans: | Mol Cancer |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252024/ https://ncbi.nlm.nih.gov/pubmed/25410152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-251 |
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