Osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection associated with delayed type I interferon responses

BACKGROUND: Arthritogenic alphaviruses such as Ross River virus (RRV) and chikungunya virus (CHIKV) have caused widespread outbreaks of chronic polyarthritis. The inflammatory responses in alphavirus-induced arthritis and osteoarthritis (OA) share many similar features, which suggests the possibilit...

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Veröffentlicht in:Virol J
Hauptverfasser: Chen, Weiqiang, Foo, Suan-Sin, Li, Rachel W, Smith, Paul N, Mahalingam, Suresh
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252017/
https://ncbi.nlm.nih.gov/pubmed/25407789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-014-0189-9
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