Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss

Arthritogenic alphaviruses including Ross River virus (RRV), Sindbis virus, and chikungunya virus cause worldwide outbreaks of musculoskeletal disease. The ability of alphaviruses to induce bone pathologies remains poorly defined. Here we show that primary human osteoblasts (hOBs) can be productivel...

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Hauptverfasser: Chen, Weiqiang, Foo, Suan-Sin, Rulli, Nestor E., Taylor, Adam, Sheng, Kuo-Ching, Herrero, Lara J., Herring, Belinda L., Lidbury, Brett A., Li, Rachel W., Walsh, Nicole C., Sims, Natalie A., Smith, Paul N., Mahalingam, Suresh
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000821/
https://ncbi.nlm.nih.gov/pubmed/24733914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318859111
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