Quantitative characterization of androgen receptor protein expression and cellular localization in circulating tumor cells from patients with metastatic castration-resistant prostate cancer

BACKGROUND: Many current therapies for metastatic castration-resistant prostate cancer (mCRPC) are aimed at AR signaling; however, resistance to these therapies is inevitable. To personalize CRPC therapy in an individual with clinical progression despite maximal AR signaling blockade, it is importan...

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Udgivet i:J Transl Med
Main Authors: Reyes, Edwin E, VanderWeele, David J, Isikbay, Masis, Duggan, Ryan, Campanile, Alexa, Stadler, Walter M, Vander Griend, Donald J, Szmulewitz, Russell Z
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252013/
https://ncbi.nlm.nih.gov/pubmed/25424879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0313-z
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