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EPR and Mössbauer Spectroscopy Show Inequivalent Hemes in Tryptophan Dioxygenase

Tryptophan 2,3-dioxygenase (TDO) is an essential enzyme in the pathway of NAD biosynthesis and important for all living organisms. TDO catalyzes oxidative cleavage of the indole ring of L-tryptophan (L-Trp), converting it to N-formylkynurenine (NFK). The crystal structure of TDO shows a dimer of dim...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Gupta, Rupal, Fu, Rong, Liu, Aimin, Hendrich, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251817/
https://ncbi.nlm.nih.gov/pubmed/20047315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908851e
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