Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model.

We have already demonstrated that a hyperinsulinemic, diabetic subject secreted an abnormal insulin in which serine replaced phenylalanine B24 (Shoelson S., M. Fickova, M. Haneda, A. Nahum, G. Musso, E. T. Kaiser, A. H. Rubenstein, and H. Tager. 1983. Proc. Natl. Acad. Sci. USA. 80:7390-7394). High...

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Pubblicato in:	J Clin Invest
Autori principali:	Shoelson, S E, Polonsky, K S, Zeidler, A, Rubenstein, A H, Tager, H S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6371057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111338
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