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Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model.

We have already demonstrated that a hyperinsulinemic, diabetic subject secreted an abnormal insulin in which serine replaced phenylalanine B24 (Shoelson S., M. Fickova, M. Haneda, A. Nahum, G. Musso, E. T. Kaiser, A. H. Rubenstein, and H. Tager. 1983. Proc. Natl. Acad. Sci. USA. 80:7390-7394). High...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Shoelson, S E, Polonsky, K S, Zeidler, A, Rubenstein, A H, Tager, H S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1984
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6371057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111338
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