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Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst

Chiral anion phase-transfer of aryldiazonium cations was utilized to achieve highly enantioselective α-amination of carbonyl compounds. A broad scope of indanone- and benzosuberone-derived substrates was amenable to this strategy. Critical to obtaining high levels of enantioselectivity was the use o...

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Библиографические подробности
Опубликовано в: :Chem Sci
Главные авторы: Nelson, H. M., Patel, J. S., Shunatona, H. P., Toste, F. D.
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251561/
https://ncbi.nlm.nih.gov/pubmed/25485073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02494j
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