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Enantioselective α-Amination of 1,3-Dicarbonyl Compounds Using Squaramide Derivatives as Hydrogen Bonding Catalysts

[Image: see text] Catalytic enantioselective α-hydrazination of 1,3-dicarbonyl compounds with azodicarboxylates was investigated in the presence of our newly developed hydrogen bonding catalyst, squaramide 3j. High yields and high enantioselectivities were achieved with low catalyst loading under mi...

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Detalhes bibliográficos
Main Authors: Konishi, Hideyuki, Lam, Tin Yiu, Malerich, Jeremiah P., Rawal, Viresh H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862278/
https://ncbi.nlm.nih.gov/pubmed/20359172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1005104
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