The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study

OBJECTIVE: Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls i...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Ann Rheum Dis
Hoofdauteurs: Panoutsopoulou, Kalliope, Metrustry, Sarah, Doherty, Sally A, Laslett, Laura L, Maciewicz, Rose A, Hart, Deborah J, Zhang, Weiya, Muir, Kenneth R, Wheeler, Margaret, Cooper, Cyrus, Spector, Tim D, Cicuttini, Flavia M, Jones, Graeme, Arden, Nigel K, Doherty, Michael, Zeggini, Eleftheria, Valdes, Ana M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2014
Onderwerpen:
Clinical and Epidemiological Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251538/
https://ncbi.nlm.nih.gov/pubmed/23921993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203772
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items