The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study

OBJECTIVE: Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Ann Rheum Dis
मुख्य लेखकों: Panoutsopoulou, Kalliope, Metrustry, Sarah, Doherty, Sally A, Laslett, Laura L, Maciewicz, Rose A, Hart, Deborah J, Zhang, Weiya, Muir, Kenneth R, Wheeler, Margaret, Cooper, Cyrus, Spector, Tim D, Cicuttini, Flavia M, Jones, Graeme, Arden, Nigel K, Doherty, Michael, Zeggini, Eleftheria, Valdes, Ana M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMJ Publishing Group 2014
विषय:
Clinical and Epidemiological Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251538/
https://ncbi.nlm.nih.gov/pubmed/23921993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203772
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