The Canadian Methotrexate and Etanercept Outcome Study: a randomised trial of discontinuing versus continuing methotrexate after 6 months of etanercept and methotrexate therapy in rheumatoid arthritis

OBJECTIVE: To determine if withdrawing methotrexate (MTX) after 6 months of combination etanercept (ETN)+MTX, in MTX-inadequate responders with active rheumatoid arthritis (RA), is non-inferior to continuing ETN+MTX. METHODS: Tumour necrosis factor-inhibitor naïve RA patients with disease activity s...

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Dades bibliogràfiques
Publicat a:Ann Rheum Dis
Autors principals: Pope, Janet E, Haraoui, Boulos, Thorne, J Carter, Vieira, Andrew, Poulin-Costello, Melanie, Keystone, Edward C
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2014
Matèries:
Clinical and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251190/
https://ncbi.nlm.nih.gov/pubmed/23979914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203684
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