Reduction in Serum Uric Acid may be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH)

Objectives The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate lowers UA in early RA (ERA). Methods Data were obtained from Canadian Early Arth...

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Main Authors: Jason J. Lee, Vivian P. Bykerk, George K. Dresser, Gilles Boire, Boulos Haraoui, Carol Hitchon, Carter Thorne, Diane Tin, Shahin Jamal, Edward C. Keystone, Janet E. Pope
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2016-01-01
Colecção:Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Acesso em linha:https://doi.org/10.4137/CMAMD.S38092
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