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Reduction in Serum Uric Acid May Be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH)

OBJECTIVES: The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate lowers UA in early RA (ERA). METHODS: Data were obtained from Canadian Early Ar...

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Vydáno v:Clin Med Insights Arthritis Musculoskelet Disord
Hlavní autoři: Lee, Jason J., Bykerk, Vivian P., Dresser, George K., Boire, Gilles, Haraoui, Boulos, Hitchon, Carol, Thorne, Carter, Tin, Diane, Jamal, Shahin, Keystone, Edward C., Pope, Janet E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Libertas Academica 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821431/
https://ncbi.nlm.nih.gov/pubmed/27081318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMAMD.S38092
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