Reduction in Serum Uric Acid May Be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH)

OBJECTIVES: The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate lowers UA in early RA (ERA). METHODS: Data were obtained from Canadian Early Ar...

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Bibliografiske detaljer
Udgivet i:Clin Med Insights Arthritis Musculoskelet Disord
Main Authors: Lee, Jason J., Bykerk, Vivian P., Dresser, George K., Boire, Gilles, Haraoui, Boulos, Hitchon, Carol, Thorne, Carter, Tin, Diane, Jamal, Shahin, Keystone, Edward C., Pope, Janet E.
Format: Artigo
Sprog:Inglês
Udgivet: Libertas Academica 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821431/
https://ncbi.nlm.nih.gov/pubmed/27081318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMAMD.S38092
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