Reduction in Serum Uric Acid May Be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH)

OBJECTIVES: The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate lowers UA in early RA (ERA). METHODS: Data were obtained from Canadian Early Ar...

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Detalhes bibliográficos
Publicado no:Clin Med Insights Arthritis Musculoskelet Disord
Main Authors: Lee, Jason J., Bykerk, Vivian P., Dresser, George K., Boire, Gilles, Haraoui, Boulos, Hitchon, Carol, Thorne, Carter, Tin, Diane, Jamal, Shahin, Keystone, Edward C., Pope, Janet E.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821431/
https://ncbi.nlm.nih.gov/pubmed/27081318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMAMD.S38092
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