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Activation of NLRP3 inflammasome by crystalline structures via cell surface contact
Crystalline structures activate the NLRP3 inflammasome, leading to the production of IL-1β, however, the molecular interactions responsible for NLRP3 activation are not fully understood. Cathepsin B release from the ruptured phagolysosome and potassium ion efflux have been suggested to be critical f...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250918/ https://ncbi.nlm.nih.gov/pubmed/25445147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07281 |
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