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Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients

PURPOSE: To evaluate the mRNA and protein expressions of NLRP3 inflammasome and its downstream inflammatory factors in human dry eye. METHODS: We recruited 54 patients with Sjögren’s syndrome dry eye (SSDE), 50 patients with non-Sjögren’s syndrome dry eye (NSSDE), and 46 healthy controls. Tear film...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Niu, Liangliang, Zhang, Shujie, Wu, Jihong, Chen, Ling, Wang, Yan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427105/
https://ncbi.nlm.nih.gov/pubmed/25962072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126277
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