Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

Dendritic cells are targeted by regulatory T (T reg) cells, in a manner that operates as an indirect mode of T cell suppression. In this study, using a combination of single-cell force spectroscopy and structured illumination microscopy, we analyze individual T reg cell–DC interaction events and sho...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chen, Jiahuan, Ganguly, Anutosh, Mucsi, Ashley D., Meng, Junchen, Yan, Jiacong, Detampel, Pascal, Munro, Fay, Zhang, Zongde, Wu, Mei, Hari, Aswin, Stenner, Melanie D., Zheng, Wencheng, Kubes, Paul, Xia, Tie, Amrein, Matthias W., Qi, Hai, Shi, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294852/
https://ncbi.nlm.nih.gov/pubmed/28082358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160620
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