Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

Dendritic cells are targeted by regulatory T (T reg) cells, in a manner that operates as an indirect mode of T cell suppression. In this study, using a combination of single-cell force spectroscopy and structured illumination microscopy, we analyze individual T reg cell–DC interaction events and sho...

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Vydáno v:J Exp Med
Hlavní autoři: Chen, Jiahuan, Ganguly, Anutosh, Mucsi, Ashley D., Meng, Junchen, Yan, Jiacong, Detampel, Pascal, Munro, Fay, Zhang, Zongde, Wu, Mei, Hari, Aswin, Stenner, Melanie D., Zheng, Wencheng, Kubes, Paul, Xia, Tie, Amrein, Matthias W., Qi, Hai, Shi, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294852/
https://ncbi.nlm.nih.gov/pubmed/28082358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160620
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