Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.

We have examined the role of the glutathione redox cycle as an antioxidant defense mechanism in cultured bovine and human endothelial cells by disrupting the glutathione redox cycle at several points. Endothelial glutathione reductase was selectively inhibited with 1,3-bis(chloroethyl)-1-nitrosourea...

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Detalhes bibliográficos
Main Authors: Harlan, J M, Levine, J D, Callahan, K S, Schwartz, B R, Harker, L A
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC425072/
https://ncbi.nlm.nih.gov/pubmed/6707200
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