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Reversal of the phenotype by K-ras(val12) silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1
AIM: To investigate the in vitro antitumor effect of adenovirus-mediated small interfering RNAs (siRNAs) on pancreatic cancer and the associated mechanism. METHODS: A 63-nucleotide (nt) oligonucleotide encoding K-ras(val12) and specific siRNA were introduced into pSilencer 3.1-H1, then the H1-RNA pr...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250591/ https://ncbi.nlm.nih.gov/pubmed/15682475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i6.831 |
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