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Complement Blockade with a C1 Esterase Inhibitor in Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, clonal, hematopoietic stem cell disorder that manifests with a complement-mediated hemolytic anemia, bone marrow failure and a propensity for thrombosis. These patients experience both intra- and extravascular hemolysis in the context of underlyin...

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Dades bibliogràfiques
Publicat a:Exp Hematol
Autors principals: DeZern, Amy E., Uknis, Marc, Yuan, Xuan, Mukhina, Galina L, Varela, Juan, Saye, JoAnne, Pu, Jeffrey, Brodsky, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250431/
https://ncbi.nlm.nih.gov/pubmed/25034232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.06.007
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