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Suppressive Oligodeoxynucleotides Promote the Generation of Regulatory T Cells by Inhibiting STAT1 Phosphorylation

Suppressive oligodeoxynucleotides (Sup ODN) express repetitive TTAGGG motifs that have proven useful in the treatment/prevention of numerous inflammatory and autoimmune diseases. The mechanism underlying the immunosuppressive activity of Sup ODN is incompletely understood. Regulatory T cells (T(reg)...

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Detalhes bibliográficos
Publicado no:Int Immunopharmacol
Main Authors: Bode, Christian, Wang, Jing, Klinman, Dennis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250357/
https://ncbi.nlm.nih.gov/pubmed/25311665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2014.09.027
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