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Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.

Patients with familial hypercholesterolemia have elevated levels of plasma low density lipoproteins (LDL), increased hepatic synthesis of apolipoprotein B-containing lipoproteins, defective binding of low density lipoproteins to fibroblasts, and premature atherosclerosis. The role of a hepatic low d...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Hoeg, J M, Demosky, S J, Schaefer, E J, Starzl, T E, Brewer, H B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425034/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111229
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