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Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemia.

Skin fibroblasts from a patient with homozygous familial hypercholesterolemia (HFH) were compared with normal skin fibroblasts with regard to binding, internalization, and degradation of iodinated human low density lipoprotein (LDL). Like other cell lines from HFH patients, the mutant cells showed n...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Stein, O, Weinstein, D B, Stein, Y, Steinberg, D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/174096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.1.14
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