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Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.

Patients with familial hypercholesterolemia have elevated levels of plasma low density lipoproteins (LDL), increased hepatic synthesis of apolipoprotein B-containing lipoproteins, defective binding of low density lipoproteins to fibroblasts, and premature atherosclerosis. The role of a hepatic low d...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Hoeg, J M, Demosky, S J, Schaefer, E J, Starzl, T E, Brewer, H B
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1984
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425034/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111229
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