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Cardiac Troponin I Tyrosine 26 Phosphorylation Decreases Myofilament Ca(2+) Sensitivity and Accelerates Deactivation
Troponin I (TnI), the inhibitory subunit of the troponin complex, can be phosphorylated as a key regulatory mechanism to alter the calcium regulation of contraction. Recent work has identified phosphorylation of TnI Tyr-26 in the human heart with unknown functional effects. We hypothesized that TnI...
Tallennettuna:
| Julkaisussa: | J Mol Cell Cardiol |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250312/ https://ncbi.nlm.nih.gov/pubmed/25252176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.09.013 |
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