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Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage

Recently, we described the existence of the ubiquitin fold modifier1 (Ufm1) and its conjugation pathway in Leishmania donovani. We demonstrated the conjugation of Ufm1 to proteins such as mitochondrial trifunctional protein (MTP) that catalyzes β-oxidation of fatty acids in L. donovani. To elucidate...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Gannavaram, Sreenivas, Connelly, Patricia S, Daniels, Mathew P, Duncan, Robert, Salotra, Poonam, Nakhasi, Hira L
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249706/
https://ncbi.nlm.nih.gov/pubmed/22897198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08183.x
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