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Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: Comparison with the cis-fused isomers
Ligands which selectively activate only one of the estrogen receptors, ERα or ERβ, are current pharmaceutical targets. Previously, we have reported on substituted cis A-CD ligands in which the B-ring of the steroidal structure has been removed and cis refers the stereochemistry of the CD ring juncti...
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| Publicado en: | Bioorg Med Chem Lett |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249688/ https://ncbi.nlm.nih.gov/pubmed/25027938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.06.066 |
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