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Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: Comparison with the cis-fused isomers

Ligands which selectively activate only one of the estrogen receptors, ERα or ERβ, are current pharmaceutical targets. Previously, we have reported on substituted cis A-CD ligands in which the B-ring of the steroidal structure has been removed and cis refers the stereochemistry of the CD ring juncti...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem Lett
Päätekijät: Dabrota, Cristian, Asim, Muhammad, Choueiri, Christine, Gargaun, Ana, Korobkov, Ilya, Butt, Ammara, Carlson, Kathryn E., Katzenellenbogen, John A., Wright, James S., Durst, Tony
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249688/
https://ncbi.nlm.nih.gov/pubmed/25027938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.06.066
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