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Cancer Cell Glycocalyx Mediates Mechanostransduction and Flow-Regulated Invasion

Mammalian cells are covered by a surface proteoglycan (glycocalyx) layer, and it is known that blood vessel-lining endothelial cells use the glycocalyx to sense and transduce the shearing forces of blood flow into intracellular signals. Tumor cells in vivo are exposed to forces from interstitial flu...

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Dades bibliogràfiques
Publicat a:Integr Biol (Camb)
Autors principals: Qazi, Henry, Palomino, Rocio, Shi, Zhong-Dong, Munn, Lance L., Tarbell, John M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249644/
https://ncbi.nlm.nih.gov/pubmed/24077103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ib40057c
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