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Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism

The migration of vascular smooth muscle cells (SMCs) and fibroblasts into the intima after vascular injury is a central process in vascular lesion formation. The elevation of transmural interstitial flow is also observed after damage to the vascular endothelium. We have previously shown that interst...

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Autors principals: Shi, Zhong-Dong, Ji, Xin-Ying, Berardi, Danielle E., Qazi, Henry, Tarbell, John M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806139/
https://ncbi.nlm.nih.gov/pubmed/19880665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00732.2009
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