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Cancer Cell Glycocalyx Mediates Mechanostransduction and Flow-Regulated Invasion
Mammalian cells are covered by a surface proteoglycan (glycocalyx) layer, and it is known that blood vessel-lining endothelial cells use the glycocalyx to sense and transduce the shearing forces of blood flow into intracellular signals. Tumor cells in vivo are exposed to forces from interstitial flu...
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| Published in: | Integr Biol (Camb) |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249644/ https://ncbi.nlm.nih.gov/pubmed/24077103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ib40057c |
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