An In Vitro Deletion in ribE Encoding Lumazine Synthase Contributes to Nitrofurantoin Resistance in Escherichia coli

Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon. Nitrofurantoin concentrations in the gastrointestinal tract tend to be low, which might facilitate selection of nitrofurantoin-resista...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Vervoort, Jascha, Xavier, Basil Britto, Stewardson, Andrew, Coenen, Samuel, Godycki-Cwirko, Maciek, Adriaenssens, Niels, Kowalczyk, Anna, Lammens, Christine, Harbarth, Stephan, Goossens, Herman, Malhotra-Kumar, Surbhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249564/
https://ncbi.nlm.nih.gov/pubmed/25246406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03952-14
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