An In Vitro Deletion in ribE Encoding Lumazine Synthase Contributes to Nitrofurantoin Resistance in Escherichia coli

Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon. Nitrofurantoin concentrations in the gastrointestinal tract tend to be low, which might facilitate selection of nitrofurantoin-resista...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vervoort, Jascha, Xavier, Basil Britto, Stewardson, Andrew, Coenen, Samuel, Godycki-Cwirko, Maciek, Adriaenssens, Niels, Kowalczyk, Anna, Lammens, Christine, Harbarth, Stephan, Goossens, Herman, Malhotra-Kumar, Surbhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249564/
https://ncbi.nlm.nih.gov/pubmed/25246406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03952-14
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