An In Vitro Deletion in ribE Encoding Lumazine Synthase Contributes to Nitrofurantoin Resistance in Escherichia coli

Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon. Nitrofurantoin concentrations in the gastrointestinal tract tend to be low, which might facilitate selection of nitrofurantoin-resista...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Vervoort, Jascha, Xavier, Basil Britto, Stewardson, Andrew, Coenen, Samuel, Godycki-Cwirko, Maciek, Adriaenssens, Niels, Kowalczyk, Anna, Lammens, Christine, Harbarth, Stephan, Goossens, Herman, Malhotra-Kumar, Surbhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249564/
https://ncbi.nlm.nih.gov/pubmed/25246406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03952-14
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