An In Vitro Deletion in ribE Encoding Lumazine Synthase Contributes to Nitrofurantoin Resistance in Escherichia coli

Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon. Nitrofurantoin concentrations in the gastrointestinal tract tend to be low, which might facilitate selection of nitrofurantoin-resista...

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Spremljeno u:
Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Vervoort, Jascha, Xavier, Basil Britto, Stewardson, Andrew, Coenen, Samuel, Godycki-Cwirko, Maciek, Adriaenssens, Niels, Kowalczyk, Anna, Lammens, Christine, Harbarth, Stephan, Goossens, Herman, Malhotra-Kumar, Surbhi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249564/
https://ncbi.nlm.nih.gov/pubmed/25246406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03952-14
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