Unexpected In Vivo Activity of Ceftazidime Alone and in Combination with Avibactam against New Delhi Metallo-β-Lactamase-Producing Enterobacteriaceae in a Murine Thigh Infection Model

The emergence of the New Delhi metallo-β-lactamase (NDM) among Enterobacteriaceae has become a global concern because of its high levels of in vitro resistance to nearly all available antibiotics. However, recent in vivo studies demonstrated the efficacies of carbapenems against NDM-1-producing isol...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: MacVane, Shawn H., Crandon, Jared L., Nichols, Wright W., Nicolau, David P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249434/
https://ncbi.nlm.nih.gov/pubmed/25223998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02662-14
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