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Understanding Variability in Posaconazole Exposure Using an Integrated Population Pharmacokinetic Analysis

Posaconazole oral suspension is widely used for antifungal prophylaxis and treatment in immunocompromised patients, with highly variable pharmacokinetics reported in patients due to inconsistent oral absorption. This study aimed to characterize the pharmacokinetics of posaconazole in adults and inve...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Dolton, Michael J., Brüggemann, Roger J. M., Burger, David M., McLachlan, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249414/
https://ncbi.nlm.nih.gov/pubmed/25199779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03777-14
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