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Understanding Variability in Posaconazole Exposure Using an Integrated Population Pharmacokinetic Analysis

Posaconazole oral suspension is widely used for antifungal prophylaxis and treatment in immunocompromised patients, with highly variable pharmacokinetics reported in patients due to inconsistent oral absorption. This study aimed to characterize the pharmacokinetics of posaconazole in adults and inve...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dolton, Michael J., Brüggemann, Roger J. M., Burger, David M., McLachlan, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249414/
https://ncbi.nlm.nih.gov/pubmed/25199779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03777-14
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