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Posaconazole Exposure-Response Relationship: Evaluating the Utility of Therapeutic Drug Monitoring

Posaconazole has become an important part of the antifungal armamentarium in the prophylaxis and salvage treatment of invasive fungal infections (IFIs). Structurally related to itraconazole, posaconazole displays low oral bioavailability due to poor solubility, with significant drug interactions and...

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Bibliografiske detaljer
Main Authors: Dolton, Michael J., Ray, John E., Marriott, Deborah, McLachlan, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370770/
https://ncbi.nlm.nih.gov/pubmed/22391534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05900-11
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