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Posaconazole Exposure-Response Relationship: Evaluating the Utility of Therapeutic Drug Monitoring

Posaconazole has become an important part of the antifungal armamentarium in the prophylaxis and salvage treatment of invasive fungal infections (IFIs). Structurally related to itraconazole, posaconazole displays low oral bioavailability due to poor solubility, with significant drug interactions and...

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Detalhes bibliográficos
Main Authors: Dolton, Michael J., Ray, John E., Marriott, Deborah, McLachlan, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370770/
https://ncbi.nlm.nih.gov/pubmed/22391534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05900-11
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